Scoliosis and spine involvement in fibrous dysplasia of bone
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چکیده
منابع مشابه
Fibrous Dysplasia of Bone
Fibrous dysplasia is a disease which may be manifested in a single bone as tumefaction or a solitary cyst (monostotic type), in a region involving contiguous bones, or in a diffuse manner (polyostotic type), the latter possibly in association with endocrine and developmental disturbances. The condition is of interest to the neurological surgeon when the cranial or cranio-facial structures are i...
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BACKGROUND Lesions of fibrous dysplasia involving the spine and scoliosis are thought to be uncommon entities in patients with polyostotic fibrous dysplasia and McCune-Albright syndrome. By examining bone scans of a relatively large cohort of patients with these disorders, we sought to determine the prevalence of spinal involvement and any association with scoliosis. METHODS Sixty-two patient...
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Fibrous dysplasia involving the thoracic spine is very rare. This patient had monostotic fibrous dysplasia involving the vertebral body, posterior elements, and right seventh rib with focal neurologic signs. The radiographic and bone scan findings are shown. The patient was treated successfully with tumor resection and arthrodesis using combined anterior and posterior approaches. Although fibro...
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Fibrous dysplasia of bone FD is caused by somatic mutations of the GNAS1. Here, patterns of osteoclastogenesis and bone resorption reflect not only the.FIBROUS DYSPLASIA FD is a sporadic developmental disorder characterized by. Biochemical indices of bone turnover are usually high particularly serum. Osteoclasts within the lesions is slightly higher than normal and the number of.Introduction: F...
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BACKGROUND Polyostotic fibrous dysplasia is a skeletal disease that results from somatic activating mutations in the gene GNAS in skeletal stem cells, leading to proliferation of immature osteogenic cells with replacement of normal marrow and bone with fibro-osseous tissue. Lesions may cause bone deformity or fracture. In the surgical care of polyostotic fibrous dysplasia, the role of grafting ...
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ژورنال
عنوان ژورنال: European Spine Journal
سال: 2009
ISSN: 0940-6719,1432-0932
DOI: 10.1007/s00586-008-0860-1